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[elyusium]

Subject:
Fwd: [en] IACM-Bulletin of 29 August 2010
From:
troberts38@comcast.net
Date:
Sun, 29 Aug 2010 19:04:47 +0000 (UTC)
To:
MAPS Forum <maps_forum@maps.org>


----- info@cannabis-med.org wrote:

     --------------------------------------------------------
     IACM-Bulletin of 29 August 2010
     --------------------------------------------------------

     * Science: Production of THC by genetically modified bacteria
     *Germany: Changes of the narcotics law to allow for the approval of
     Sativex intended
     * Germany: Federal Institute for Drugs and Medical Devices rejects
     application for self-cultivation of cannabis for medicinal purposes
     * USA/The Netherlands: The cannabis grower Bedrocan goes
     international and intends to get approval by US health authorities in
     the long run

     1.

     Science: Production of THC by genetically modified bacteria

     Scientists of the Technical University of Dortmund, Germany, have
     genetically manipulated bacteria in a manner that allows them to
     produce the main psychoactive compound of cannabis. This
     procedure for the production of THC (dronabinol) is thought to be
     less laborious and therefore cheaper in comparison to the currently
     used procedure in Germany, said Oliver Kayser of the university on
     17 August.

     To date, dronabinol has been produced from fibre hemp in
     Germany. Cannabidiol (CBD) is extracted from this hemp and
     converted into THC. Chemical extraction from THC-rich drug hemp
     is not allowed in Germany. The synthetic manufacture of dronabinol
     would also be costly in comparison to the new procedure. Kayser
     is anticipating production costs with the new procedure of only
     about 2,500 Euros per kilogram of THC. E. coli bacteria with
     isolated genes are responsible for the production of THC in the
     plant are used. Together with a pharmaceutical company, the
     University of Dortmund is planning the foundation of a company for
     THC production.

     More at:
     http://derstandard.at/1281829392202/Tetrahydrocannabinol-
     Bakterien-koennen-ohne-viel-Aufwand-Cannabis-Wirkstoff-
     produzieren

     (Source: Standard of 17 August 2010)
 

[elyusium]

Marijuana Compound Halts Breast Cancer Tumor Growth

Madrid, Spain: The administration of THC reduces the tumor growth of metastatic breast cancer and "might constitute a new therapeutic tool for the treatment" of cancerous tumors, according to preclinical data published online in the journal Molecular Cancer.

Investigators from Complutense University in Madrid assessed the anti-tumor potential of THC and JWH-133, a non-psychotropic CB2 receptor-selective agonist, in the treatment of ErbB2-positive breast tumors – a highly aggressive form of breast cancer that is typically unresponsive to standard therapies.

Researchers reported, "oth Delta-9-tetrahydrocannabinol ... and JWH-133 ...reduce tumor growth [and] tumor number [in mice]. ... [T]hese results provide a strong preclinical evidence for the use of cannabinoid-based therapies for the management of ErbB2-positive breast cancer."

In 2007, investigators at the California Pacific Medical Center Research Institute reported that the administration of the nonpsychoactive cannabinoid CBD limited breast cancer metastasis in a manner that was superior to comparable synthesized agents.

Previous preclinical studies assessing the anticancer properties of cannabinoids have shown that they inhibit the proliferation of a wide range of cancers, including brain cancer, prostate cancer, oral cancers, lung cancer, skin cancer, pancreatic cancer, biliary tract cancers, and lymphoma.

For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, "Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition," is available online at: http://www.molecular-cancer.com/content/9/1/196.

[jbmac]

I tell people it's the same plant, when it grows naturally it's hemp. When you take away all the male plants, you get pot.

[Hempity]

Thanks Hempity. Wasn't sure about the Jah (my term for the entity in the plant) connection on a hemp site. Truth is, what I know about hemp is what everyone knows who has looked into it. Nothing new to share there after science perfected the retting process. The newest news and empirical studies are finally being done with psychoactive cannabis. So lets see if I have this straight, or as straight as I get: Cannabis is both hemp and marijuana? Is that correct, as a gardener I should know this and do know where to find it, but it's fun asking on site. Or is Hemp Marijuana? Is hemp simply the term used to identify non-psychoactive marijuana?
  

Sea Mac is right(good to see you both)
It all has to do with terminology and what it is used for.
They are the same plant, just more or lesser cannabinoids.
The higher cannabinoid of delta 9 plant is the one we use for medication and to me
recreation is part of any good medical plan.
This plant also has fibre, hurd and can have seed, just not as much as the lower cannabinoid.
Seems to me one plant should be able to give it all to us, in fact natives say it is our buffalo.
After growing so much of it, I believe it with all my heart.
We used the hurd for bricks, and for filling between logs on a log home, it was hard as concrete and as  light as wood, in fact it petrifies.
 

[Sea Mac]

Welcome to the Forum, Buddy!
 
It's good to have another concerned activist of your caliber on board.

Hemp usually refers to any non-marijuana use for the Cannabis plant. Marijuana usually refers to recreational or medical use of the leaves and (primarily) flowers of the same plant. If the Government LEGALIZED Uses for Hemp such as Rope/Canvas/Fabrics/Fibers/Hemp oil from seeds/Bio-Diesel from said oil/and so on: it could bring millions of new jobs in these tight economic times - right now!

But you just KNOW that lobbyists from the timber and oil industries would rather protect their interests: even at the expense of the economy!

[elyusium]

Thanks Hempity. Wasn't sure about the Jah (my term for the entity in the plant) connection on a hemp site. Truth is, what I know about hemp is what everyone knows who has looked into it. Nothing new to share there after science perfected the retting process. The newest news and empirical studies are finally being done with psychoactive cannabis. So lets see if I have this straight, or as straight as I get: Cannabis is both hemp and marijuana? Is that correct, as a gardener I should know this and do know where to find it, but it's fun asking on site. Or is Hemp Marijuana? Is hemp simply the term used to identify non-psychoactive marijuana?
  

[Hempity]

Unless the big boss says different.
This is absoulty the right place for this kind of discussion.
My friends DdC and FoM have an incredible amount of links between them, for research and uses.
FoM's site http://www.cannabisnews.com and I don't remember DdC's but it should be on one of his posts. Or in his profile.
We have known each other on line, and been knee deep in the 'war on people' for fifteen or more years.

[elyusium]

I hope this is the right place for this, my first post so I'm a bit uncertain where to put things so far. I wanted to start a Topic on studies using marijuana as medicine. Is it alright to speak about this here?

from IACM Bulletin--


Science: Cannabis effective in the treatment of Tourette
Syndrome and attention deficit hyperactivity disorder (ADHD)

German scientists from the universities of Goettingen, Hamburg
and Dresden reported of the treatment of a 15-year-old boy with
treatment refractory Tourette Syndrome (TS) and attention deficit
hyperactivity disorder (ADHD) leading to severe physical and
psychosocial impairment. Administration of THC resulted in a
considerable improvement of tics without adverse effects,
allowing parallel stimulant treatment of comorbid ADHD. Along
with THC treatment, intracortical inhibition, that is inhibition of
signal transmission between nerve cells in the cortex of the brain,
was increased.

Authors concluded that "our observation suggests that delta-9-
THC might be a successful alternative in patients with severe TS
refractory to classic treatment. Particularly in the case of
stimulant-induced exacerbation of tics, delta-9-THC might enable
successful treatment of comorbid ADHD. The enhancement of
intracortical inhibition might be mediated by modulating release of
several neurotransmitters including dopamine and gamma-
aminobutyric acid."

(Source: Hasan A, Rothenberger A, Münchau A, Wobrock T,
Falkai P, Roessner V. Oral delta9-tetrahydrocannabinol improved
refractory gilles de la tourette syndrome in an adolescent by
increasing intracortical inhibition: a case report. J Clin
Psychopharmacol 2010;30(2):190-2.)